Some features of soft tissue regeneration when using scaffolds made of synthetic and various types of xenonogenic materials (literature review) 

Oleg V. Kalmin, Doctor of medical sciences, professor, head of the sub-department of human anatomy, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: kalmin_ov@pnzgu.ru
Marija G. Fedorova, Candidate of medical sciences, associate professor, head of the sub-department of morphology, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: fedorovamerry@gmail.com
Ekaterina V. Komarova, Candidate of biological sciences, associate professor of the sub-department of morphology, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: ekaterina-log@inbox.ru
Nikita O. Tsyplikhin, Resident of the sub-department of morphology, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia)
Anna M. Mikheeva, Student, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: miheevaa695@gmail.com 

In modern medicine, the issues of regeneration of damaged organs are quite relevant. Methods are being actively developed to simplify regeneration processes. The object of study is scaffolds, that is, structures of various materials that serve as a substrate for tissue regeneration. Tissue engineering is involved in the development of such structures. It combines the scientific achievements of cell biology, biochemistry, engineering and medicine. New methods for producing scaffolds are being developed. Thus, scaffolds are a polymer or other composite material that can imitate the structure of various tissues; it contains healing drugs. Scaffolds are cellular matrices, the main part of which is tissue regeneration. Next, this study provides a review of the literature on the benefits and practices of using scaffolds made of synthetic and various xenogeneic materials in regenerative medicine. 

scaffold, collagen, fibroin, synthetic materials, regeneration, morphology 

Kalmin O.V., Fedorova M.G., Komarova E.V., Tsyplikhin N.O., Mikheeva A.M. Some features of soft tissue regeneration when using scaffolds made of synthetic and various types of xenonogenic materials (literature review). Izvestiya vysshikh uchebnykh zavedeniy. Povolzhskiy region. Meditsinskie nauki = University proceedings. Volga region. Medical sciences. 2024;(2):138–151. (In Russ.). doi: 10.21685/2072-3032-2024-2-13